Review




Structured Review

STEMCELL Technologies Inc stemspan serum-free expansion medium 09650
Stemspan Serum Free Expansion Medium 09650, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/stemspan+serum+free+expansion+medium/pm40670787-630-5-12
Average 90 stars, based on 1 article reviews
stemspan serum-free expansion medium 09650 - by Bioz Stars, 2026-09
90/100 stars

Images

Related Articles

Cell Culture:

Article Title: Dynamic assessment of myelofibrosis progression in myeloproliferative neoplasm mouse model using a minimally invasive evaluation system.
Article Snippet: Myelofibrosis (MF) is the most common complication of myeloproliferative neoplasms (MPNs),which is markedly correlated with a dismal prognosis.. Murine model such as the thrombopoietin receptor (MPL)W515Lmutant MPN mouse model functions as a crucial vehicle in disease research, is widely used in basic and applied research on MPNs and MF.However, the lack of methods for dynamic observation of MF progression hinders mechanistic studies and drug development for MF.. Here we develop a sensitive, stable and minimally invasive MPN evaluation system to assess the evolution of myelofibrosis in murine model.Key peripheral blood parameters (WBC, RBC, HGB, HCT, PLT, and tumor cell proportion) from MPN mice were analyzed using PCA to reduce dimensionality and generate a comprehensive evaluation score (Y).

Article Title: Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8 + T cell function through galectin-9
Article Snippet: For the first 6 weeks, CD133 + cells were cultured in serum-free expansion medium (StemCell, Canada) supplemented with penicillin (100 U/mL)/streptomycin (100 μg/mL), human recombinant (hr) IL-3 (30 ng/mL, only present during the first 3 weeks), hr IL-6 (50 ng/mL), and stem cell factor (SCF) (100 ng/mL).

Article Title: MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
Article Snippet: Serum-free expansion medium (StemCell Technologies, Canada) was used in the cultivation of CD34 + cells.

Article Title: Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Article Snippet: LSK cells were purified as described above, counted and 5,500 cells were added to a 96-well U-bottom suspension culture plate (GenClone, 25-224) and allowed to recover in broad myeloid differentiation media consisting of serum-free expansion medium (STEMCELL), penicillin–streptomycin (Pen–Strep), interleukin (IL)-3 (PeproTech, 213-13; 20 ng ml −1 ), FLT3-L (PeproTech, 250-31L; 50 ng ml −1 ), IL-11 (PeproTech, 220-11; 50 ng ml −1 ), IL-5 (PeproTech, 215-15; 10 ng ml −1 ), erythropoietin (PeproTech, 100-64; 3 U ml −1 ), thrombopoietin (PeproTech, 315-14; 50 ng ml −1 ) and mouse stem cell factor (R&D Systems, Q78ED8; 50 ng ml −1 ) and IL-6 (R&D Systems, 406-ML-005; 10 ng ml −1 ) at 37 °C for 2 h. To allow clone tracking, cells were transduced for 2 d with 10 μl of concentrated CellTag-multi virus (~25 k unique CellTag sequences) in 100 μl differentiation media, in the presence of 6 μg ml −1 diethylaminoethyl–Dextran after spin-fection at 800 g for 90 min at 37 °C.

Article Title: NEUROBEACHIN regulates hematopoietic progenitor differentiation and survival by modulating NOTCH activity.
Article Snippet: Miguel Ganuza Fernandez (Barts Centre Cancer Research UK, United Kingdom) Antonio Morales-Hernandez (University of Michigan, United States) Alanna Van Huizen (St. Jude Children's Research Hospital, United States) Ashley Chabot (St.Jude Children's Research Hospital, United States) Trent Hall (St. Jude Children's Research Hospital, ) Claire Caprio (St. Jude Children's Research Hospital, United States) David Finkelstein (SJCRH, United States) Shannon McKinney Freeman (St. Jude Children's Research Hospital, United States)

Article Title: TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Article Snippet: With the increasing use of CRISPR–Cas9, detecting off-target events is essential for safety.. Current methods primarily focus on guide RNA (gRNA) sequence mismatches, often overlooking the impact of DNA topology in regulating off-target activity.. Here we present TOPO-seq, a high-throughput and sensitive method that identifies genome-wide off-target effects of Cas9 and base editors while accounting for DNA topology.

Article Title: HSPA9 /mortalin inhibition disrupts erythroid maturation through a TP53 -dependent mechanism in human CD34+ hematopoietic progenitor cells
Article Snippet: The cells were subsequently cultured for 5 days in erythroid differentiation media containing serum-free expansion medium (STEMCell Technologies, Inc., Vancouver, Canada), human cytokines (PeproTech, Inc.) including 25 ng/mL of stem cell factor, 10 ng/mL of IL-3, 10 ng/mL of IL-6, 3 units/mL of erythropoietin, 100 U/mL of penicillin/streptomycin, and 2 mM of L -glutamine (Sigma-Aldrich Inc.).

Article Title: Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity
Article Snippet: HSPCs were cultured in serum-free expansion medium (Stem Cell Technologies, Vancouver, BC, Canada) with 10 ng/mL recombinant murine (rm) stem cell factor, 20 ng/mL rm thrombopoietin, 20 ng/mL rm insulin-like growth factor 2 (Peprotech, Rocky Hill, NJ), and 10 ng/mL recombinant human fibroblast growth factor 1 (R&D Systems, Minneapolis, MN).

Recombinant:

Article Title: Dynamic assessment of myelofibrosis progression in myeloproliferative neoplasm mouse model using a minimally invasive evaluation system.
Article Snippet: Myelofibrosis (MF) is the most common complication of myeloproliferative neoplasms (MPNs),which is markedly correlated with a dismal prognosis.. Murine model such as the thrombopoietin receptor (MPL)W515Lmutant MPN mouse model functions as a crucial vehicle in disease research, is widely used in basic and applied research on MPNs and MF.However, the lack of methods for dynamic observation of MF progression hinders mechanistic studies and drug development for MF.. Here we develop a sensitive, stable and minimally invasive MPN evaluation system to assess the evolution of myelofibrosis in murine model.Key peripheral blood parameters (WBC, RBC, HGB, HCT, PLT, and tumor cell proportion) from MPN mice were analyzed using PCA to reduce dimensionality and generate a comprehensive evaluation score (Y).

Article Title: Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8 + T cell function through galectin-9
Article Snippet: For the first 6 weeks, CD133 + cells were cultured in serum-free expansion medium (StemCell, Canada) supplemented with penicillin (100 U/mL)/streptomycin (100 μg/mL), human recombinant (hr) IL-3 (30 ng/mL, only present during the first 3 weeks), hr IL-6 (50 ng/mL), and stem cell factor (SCF) (100 ng/mL).

Article Title: MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
Article Snippet: Serum-free expansion medium (StemCell Technologies, Canada) was used in the cultivation of CD34 + cells.

Article Title: Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Article Snippet: LSK cells were purified as described above, counted and 5,500 cells were added to a 96-well U-bottom suspension culture plate (GenClone, 25-224) and allowed to recover in broad myeloid differentiation media consisting of serum-free expansion medium (STEMCELL), penicillin–streptomycin (Pen–Strep), interleukin (IL)-3 (PeproTech, 213-13; 20 ng ml −1 ), FLT3-L (PeproTech, 250-31L; 50 ng ml −1 ), IL-11 (PeproTech, 220-11; 50 ng ml −1 ), IL-5 (PeproTech, 215-15; 10 ng ml −1 ), erythropoietin (PeproTech, 100-64; 3 U ml −1 ), thrombopoietin (PeproTech, 315-14; 50 ng ml −1 ) and mouse stem cell factor (R&D Systems, Q78ED8; 50 ng ml −1 ) and IL-6 (R&D Systems, 406-ML-005; 10 ng ml −1 ) at 37 °C for 2 h. To allow clone tracking, cells were transduced for 2 d with 10 μl of concentrated CellTag-multi virus (~25 k unique CellTag sequences) in 100 μl differentiation media, in the presence of 6 μg ml −1 diethylaminoethyl–Dextran after spin-fection at 800 g for 90 min at 37 °C.

Article Title: NEUROBEACHIN regulates hematopoietic progenitor differentiation and survival by modulating NOTCH activity.
Article Snippet: Miguel Ganuza Fernandez (Barts Centre Cancer Research UK, United Kingdom) Antonio Morales-Hernandez (University of Michigan, United States) Alanna Van Huizen (St. Jude Children's Research Hospital, United States) Ashley Chabot (St.Jude Children's Research Hospital, United States) Trent Hall (St. Jude Children's Research Hospital, ) Claire Caprio (St. Jude Children's Research Hospital, United States) David Finkelstein (SJCRH, United States) Shannon McKinney Freeman (St. Jude Children's Research Hospital, United States)

Article Title: TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Article Snippet: With the increasing use of CRISPR–Cas9, detecting off-target events is essential for safety.. Current methods primarily focus on guide RNA (gRNA) sequence mismatches, often overlooking the impact of DNA topology in regulating off-target activity.. Here we present TOPO-seq, a high-throughput and sensitive method that identifies genome-wide off-target effects of Cas9 and base editors while accounting for DNA topology.

Article Title: HSPA9 /mortalin inhibition disrupts erythroid maturation through a TP53 -dependent mechanism in human CD34+ hematopoietic progenitor cells
Article Snippet: The cells were subsequently cultured for 5 days in erythroid differentiation media containing serum-free expansion medium (STEMCell Technologies, Inc., Vancouver, Canada), human cytokines (PeproTech, Inc.) including 25 ng/mL of stem cell factor, 10 ng/mL of IL-3, 10 ng/mL of IL-6, 3 units/mL of erythropoietin, 100 U/mL of penicillin/streptomycin, and 2 mM of L -glutamine (Sigma-Aldrich Inc.).

Article Title: Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity
Article Snippet: HSPCs were cultured in serum-free expansion medium (Stem Cell Technologies, Vancouver, BC, Canada) with 10 ng/mL recombinant murine (rm) stem cell factor, 20 ng/mL rm thrombopoietin, 20 ng/mL rm insulin-like growth factor 2 (Peprotech, Rocky Hill, NJ), and 10 ng/mL recombinant human fibroblast growth factor 1 (R&D Systems, Minneapolis, MN).

Purification:

Article Title: Dynamic assessment of myelofibrosis progression in myeloproliferative neoplasm mouse model using a minimally invasive evaluation system.
Article Snippet: Myelofibrosis (MF) is the most common complication of myeloproliferative neoplasms (MPNs),which is markedly correlated with a dismal prognosis.. Murine model such as the thrombopoietin receptor (MPL)W515Lmutant MPN mouse model functions as a crucial vehicle in disease research, is widely used in basic and applied research on MPNs and MF.However, the lack of methods for dynamic observation of MF progression hinders mechanistic studies and drug development for MF.. Here we develop a sensitive, stable and minimally invasive MPN evaluation system to assess the evolution of myelofibrosis in murine model.Key peripheral blood parameters (WBC, RBC, HGB, HCT, PLT, and tumor cell proportion) from MPN mice were analyzed using PCA to reduce dimensionality and generate a comprehensive evaluation score (Y).

Article Title: Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8 + T cell function through galectin-9
Article Snippet: For the first 6 weeks, CD133 + cells were cultured in serum-free expansion medium (StemCell, Canada) supplemented with penicillin (100 U/mL)/streptomycin (100 μg/mL), human recombinant (hr) IL-3 (30 ng/mL, only present during the first 3 weeks), hr IL-6 (50 ng/mL), and stem cell factor (SCF) (100 ng/mL).

Article Title: MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
Article Snippet: Serum-free expansion medium (StemCell Technologies, Canada) was used in the cultivation of CD34 + cells.

Article Title: Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Article Snippet: LSK cells were purified as described above, counted and 5,500 cells were added to a 96-well U-bottom suspension culture plate (GenClone, 25-224) and allowed to recover in broad myeloid differentiation media consisting of serum-free expansion medium (STEMCELL), penicillin–streptomycin (Pen–Strep), interleukin (IL)-3 (PeproTech, 213-13; 20 ng ml −1 ), FLT3-L (PeproTech, 250-31L; 50 ng ml −1 ), IL-11 (PeproTech, 220-11; 50 ng ml −1 ), IL-5 (PeproTech, 215-15; 10 ng ml −1 ), erythropoietin (PeproTech, 100-64; 3 U ml −1 ), thrombopoietin (PeproTech, 315-14; 50 ng ml −1 ) and mouse stem cell factor (R&D Systems, Q78ED8; 50 ng ml −1 ) and IL-6 (R&D Systems, 406-ML-005; 10 ng ml −1 ) at 37 °C for 2 h. To allow clone tracking, cells were transduced for 2 d with 10 μl of concentrated CellTag-multi virus (~25 k unique CellTag sequences) in 100 μl differentiation media, in the presence of 6 μg ml −1 diethylaminoethyl–Dextran after spin-fection at 800 g for 90 min at 37 °C.

Article Title: NEUROBEACHIN regulates hematopoietic progenitor differentiation and survival by modulating NOTCH activity.
Article Snippet: Miguel Ganuza Fernandez (Barts Centre Cancer Research UK, United Kingdom) Antonio Morales-Hernandez (University of Michigan, United States) Alanna Van Huizen (St. Jude Children's Research Hospital, United States) Ashley Chabot (St.Jude Children's Research Hospital, United States) Trent Hall (St. Jude Children's Research Hospital, ) Claire Caprio (St. Jude Children's Research Hospital, United States) David Finkelstein (SJCRH, United States) Shannon McKinney Freeman (St. Jude Children's Research Hospital, United States)

Article Title: TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Article Snippet: With the increasing use of CRISPR–Cas9, detecting off-target events is essential for safety.. Current methods primarily focus on guide RNA (gRNA) sequence mismatches, often overlooking the impact of DNA topology in regulating off-target activity.. Here we present TOPO-seq, a high-throughput and sensitive method that identifies genome-wide off-target effects of Cas9 and base editors while accounting for DNA topology.

Article Title: HSPA9 /mortalin inhibition disrupts erythroid maturation through a TP53 -dependent mechanism in human CD34+ hematopoietic progenitor cells
Article Snippet: The cells were subsequently cultured for 5 days in erythroid differentiation media containing serum-free expansion medium (STEMCell Technologies, Inc., Vancouver, Canada), human cytokines (PeproTech, Inc.) including 25 ng/mL of stem cell factor, 10 ng/mL of IL-3, 10 ng/mL of IL-6, 3 units/mL of erythropoietin, 100 U/mL of penicillin/streptomycin, and 2 mM of L -glutamine (Sigma-Aldrich Inc.).

Article Title: Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity
Article Snippet: HSPCs were cultured in serum-free expansion medium (Stem Cell Technologies, Vancouver, BC, Canada) with 10 ng/mL recombinant murine (rm) stem cell factor, 20 ng/mL rm thrombopoietin, 20 ng/mL rm insulin-like growth factor 2 (Peprotech, Rocky Hill, NJ), and 10 ng/mL recombinant human fibroblast growth factor 1 (R&D Systems, Minneapolis, MN).

Suspension:

Article Title: Dynamic assessment of myelofibrosis progression in myeloproliferative neoplasm mouse model using a minimally invasive evaluation system.
Article Snippet: Myelofibrosis (MF) is the most common complication of myeloproliferative neoplasms (MPNs),which is markedly correlated with a dismal prognosis.. Murine model such as the thrombopoietin receptor (MPL)W515Lmutant MPN mouse model functions as a crucial vehicle in disease research, is widely used in basic and applied research on MPNs and MF.However, the lack of methods for dynamic observation of MF progression hinders mechanistic studies and drug development for MF.. Here we develop a sensitive, stable and minimally invasive MPN evaluation system to assess the evolution of myelofibrosis in murine model.Key peripheral blood parameters (WBC, RBC, HGB, HCT, PLT, and tumor cell proportion) from MPN mice were analyzed using PCA to reduce dimensionality and generate a comprehensive evaluation score (Y).

Article Title: Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8 + T cell function through galectin-9
Article Snippet: For the first 6 weeks, CD133 + cells were cultured in serum-free expansion medium (StemCell, Canada) supplemented with penicillin (100 U/mL)/streptomycin (100 μg/mL), human recombinant (hr) IL-3 (30 ng/mL, only present during the first 3 weeks), hr IL-6 (50 ng/mL), and stem cell factor (SCF) (100 ng/mL).

Article Title: MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
Article Snippet: Serum-free expansion medium (StemCell Technologies, Canada) was used in the cultivation of CD34 + cells.

Article Title: Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Article Snippet: LSK cells were purified as described above, counted and 5,500 cells were added to a 96-well U-bottom suspension culture plate (GenClone, 25-224) and allowed to recover in broad myeloid differentiation media consisting of serum-free expansion medium (STEMCELL), penicillin–streptomycin (Pen–Strep), interleukin (IL)-3 (PeproTech, 213-13; 20 ng ml −1 ), FLT3-L (PeproTech, 250-31L; 50 ng ml −1 ), IL-11 (PeproTech, 220-11; 50 ng ml −1 ), IL-5 (PeproTech, 215-15; 10 ng ml −1 ), erythropoietin (PeproTech, 100-64; 3 U ml −1 ), thrombopoietin (PeproTech, 315-14; 50 ng ml −1 ) and mouse stem cell factor (R&D Systems, Q78ED8; 50 ng ml −1 ) and IL-6 (R&D Systems, 406-ML-005; 10 ng ml −1 ) at 37 °C for 2 h. To allow clone tracking, cells were transduced for 2 d with 10 μl of concentrated CellTag-multi virus (~25 k unique CellTag sequences) in 100 μl differentiation media, in the presence of 6 μg ml −1 diethylaminoethyl–Dextran after spin-fection at 800 g for 90 min at 37 °C.

Article Title: NEUROBEACHIN regulates hematopoietic progenitor differentiation and survival by modulating NOTCH activity.
Article Snippet: Miguel Ganuza Fernandez (Barts Centre Cancer Research UK, United Kingdom) Antonio Morales-Hernandez (University of Michigan, United States) Alanna Van Huizen (St. Jude Children's Research Hospital, United States) Ashley Chabot (St.Jude Children's Research Hospital, United States) Trent Hall (St. Jude Children's Research Hospital, ) Claire Caprio (St. Jude Children's Research Hospital, United States) David Finkelstein (SJCRH, United States) Shannon McKinney Freeman (St. Jude Children's Research Hospital, United States)

Article Title: TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Article Snippet: With the increasing use of CRISPR–Cas9, detecting off-target events is essential for safety.. Current methods primarily focus on guide RNA (gRNA) sequence mismatches, often overlooking the impact of DNA topology in regulating off-target activity.. Here we present TOPO-seq, a high-throughput and sensitive method that identifies genome-wide off-target effects of Cas9 and base editors while accounting for DNA topology.

Article Title: HSPA9 /mortalin inhibition disrupts erythroid maturation through a TP53 -dependent mechanism in human CD34+ hematopoietic progenitor cells
Article Snippet: The cells were subsequently cultured for 5 days in erythroid differentiation media containing serum-free expansion medium (STEMCell Technologies, Inc., Vancouver, Canada), human cytokines (PeproTech, Inc.) including 25 ng/mL of stem cell factor, 10 ng/mL of IL-3, 10 ng/mL of IL-6, 3 units/mL of erythropoietin, 100 U/mL of penicillin/streptomycin, and 2 mM of L -glutamine (Sigma-Aldrich Inc.).

Article Title: Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity
Article Snippet: HSPCs were cultured in serum-free expansion medium (Stem Cell Technologies, Vancouver, BC, Canada) with 10 ng/mL recombinant murine (rm) stem cell factor, 20 ng/mL rm thrombopoietin, 20 ng/mL rm insulin-like growth factor 2 (Peprotech, Rocky Hill, NJ), and 10 ng/mL recombinant human fibroblast growth factor 1 (R&D Systems, Minneapolis, MN).

Virus:

Article Title: Dynamic assessment of myelofibrosis progression in myeloproliferative neoplasm mouse model using a minimally invasive evaluation system.
Article Snippet: Myelofibrosis (MF) is the most common complication of myeloproliferative neoplasms (MPNs),which is markedly correlated with a dismal prognosis.. Murine model such as the thrombopoietin receptor (MPL)W515Lmutant MPN mouse model functions as a crucial vehicle in disease research, is widely used in basic and applied research on MPNs and MF.However, the lack of methods for dynamic observation of MF progression hinders mechanistic studies and drug development for MF.. Here we develop a sensitive, stable and minimally invasive MPN evaluation system to assess the evolution of myelofibrosis in murine model.Key peripheral blood parameters (WBC, RBC, HGB, HCT, PLT, and tumor cell proportion) from MPN mice were analyzed using PCA to reduce dimensionality and generate a comprehensive evaluation score (Y).

Article Title: Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8 + T cell function through galectin-9
Article Snippet: For the first 6 weeks, CD133 + cells were cultured in serum-free expansion medium (StemCell, Canada) supplemented with penicillin (100 U/mL)/streptomycin (100 μg/mL), human recombinant (hr) IL-3 (30 ng/mL, only present during the first 3 weeks), hr IL-6 (50 ng/mL), and stem cell factor (SCF) (100 ng/mL).

Article Title: MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
Article Snippet: Serum-free expansion medium (StemCell Technologies, Canada) was used in the cultivation of CD34 + cells.

Article Title: Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes
Article Snippet: LSK cells were purified as described above, counted and 5,500 cells were added to a 96-well U-bottom suspension culture plate (GenClone, 25-224) and allowed to recover in broad myeloid differentiation media consisting of serum-free expansion medium (STEMCELL), penicillin–streptomycin (Pen–Strep), interleukin (IL)-3 (PeproTech, 213-13; 20 ng ml −1 ), FLT3-L (PeproTech, 250-31L; 50 ng ml −1 ), IL-11 (PeproTech, 220-11; 50 ng ml −1 ), IL-5 (PeproTech, 215-15; 10 ng ml −1 ), erythropoietin (PeproTech, 100-64; 3 U ml −1 ), thrombopoietin (PeproTech, 315-14; 50 ng ml −1 ) and mouse stem cell factor (R&D Systems, Q78ED8; 50 ng ml −1 ) and IL-6 (R&D Systems, 406-ML-005; 10 ng ml −1 ) at 37 °C for 2 h. To allow clone tracking, cells were transduced for 2 d with 10 μl of concentrated CellTag-multi virus (~25 k unique CellTag sequences) in 100 μl differentiation media, in the presence of 6 μg ml −1 diethylaminoethyl–Dextran after spin-fection at 800 g for 90 min at 37 °C.

Article Title: NEUROBEACHIN regulates hematopoietic progenitor differentiation and survival by modulating NOTCH activity.
Article Snippet: Miguel Ganuza Fernandez (Barts Centre Cancer Research UK, United Kingdom) Antonio Morales-Hernandez (University of Michigan, United States) Alanna Van Huizen (St. Jude Children's Research Hospital, United States) Ashley Chabot (St.Jude Children's Research Hospital, United States) Trent Hall (St. Jude Children's Research Hospital, ) Claire Caprio (St. Jude Children's Research Hospital, United States) David Finkelstein (SJCRH, United States) Shannon McKinney Freeman (St. Jude Children's Research Hospital, United States)

Article Title: TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors.
Article Snippet: With the increasing use of CRISPR–Cas9, detecting off-target events is essential for safety.. Current methods primarily focus on guide RNA (gRNA) sequence mismatches, often overlooking the impact of DNA topology in regulating off-target activity.. Here we present TOPO-seq, a high-throughput and sensitive method that identifies genome-wide off-target effects of Cas9 and base editors while accounting for DNA topology.

Article Title: HSPA9 /mortalin inhibition disrupts erythroid maturation through a TP53 -dependent mechanism in human CD34+ hematopoietic progenitor cells
Article Snippet: The cells were subsequently cultured for 5 days in erythroid differentiation media containing serum-free expansion medium (STEMCell Technologies, Inc., Vancouver, Canada), human cytokines (PeproTech, Inc.) including 25 ng/mL of stem cell factor, 10 ng/mL of IL-3, 10 ng/mL of IL-6, 3 units/mL of erythropoietin, 100 U/mL of penicillin/streptomycin, and 2 mM of L -glutamine (Sigma-Aldrich Inc.).

Article Title: Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity
Article Snippet: HSPCs were cultured in serum-free expansion medium (Stem Cell Technologies, Vancouver, BC, Canada) with 10 ng/mL recombinant murine (rm) stem cell factor, 20 ng/mL rm thrombopoietin, 20 ng/mL rm insulin-like growth factor 2 (Peprotech, Rocky Hill, NJ), and 10 ng/mL recombinant human fibroblast growth factor 1 (R&D Systems, Minneapolis, MN).



Similar Products

90
STEMCELL Technologies Inc stemspan serum-free expansion medium 09650
Stemspan Serum Free Expansion Medium 09650, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/stemspan+serum+free+expansion+medium/pm40670787-630-5-12
Average 90 stars, based on 1 article reviews
stemspan serum-free expansion medium 09650 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
STEMCELL Technologies Inc stemspantm serum-free expansion medium
Stemspantm Serum Free Expansion Medium, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/stemspantm+serum+free+expansion+medium++sfem+/pm40597397-103-7-12
Average 90 stars, based on 1 article reviews
stemspantm serum-free expansion medium - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
STEMCELL Technologies Inc stemspantm serum-free expansion medium (sfem)
Stemspantm Serum Free Expansion Medium (Sfem), supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/stemspantm+serum+free+expansion+medium++sfem+/pmc12210517-84-11-16
Average 90 stars, based on 1 article reviews
stemspantm serum-free expansion medium (sfem) - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

93
R&D Systems human msc expansion medium
Human Msc Expansion Medium, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/StemXVivo+Serum-Free+Human+MSC+Expansion+Media/pmc12327864-37-8-13
Average 93 stars, based on 1 article reviews
human msc expansion medium - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

90
STEMCELL Technologies Inc stemspan serum-free expansion medium
Stemspan Serum Free Expansion Medium, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/serum-free+expansion+medium/stemspan+serum+free+expansion+medium/pm40588527-71-18-22
Average 90 stars, based on 1 article reviews
stemspan serum-free expansion medium - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results